Comparison between herbs used for the treatment of gastroesophageal reflux diseases(GERD)

Background:An abnormality that causes reflux is termed as Gastroesophageal reflux disease (GERD), which is symptomatic by nature and adds to the long-term effects.Objective:The aim of this study is to observe and monitor the effects of a herbal ttratment of GERD with SiniZuojin Decoction (SNZID)and to assess its mediation impacts regarding the use of the medication in patients with Gastrointestinal EBB ailment.Materials and Methods:The cohort research methodology was used inthe study.The research included 2581 individual patients who were older than 18 years of age and were suffering from Gastrointestinal ebbailment. The patients were selected from various government herbal clinics in eastern China, including the states of Anhui, Fujian, Jiangsu, Jiangxi, Shandong, and Zhejiangover, from 2008 to 2018. Results:The study was conducted with a total of 2581 patients. The thorough assessment indicated that Sini Zuojin Decoction (SZD)notwithstanding standard stomach remedies pack was more effective than the traditionalist stomach suppositories bundle (RR=1.34, with CI=95% [1.47, 1.38], and P-value = 0.008); Test packs including SZD was essentially better contrasted with traditional stomach medicines(TSM)gearshifts in developing dyspepsia, substernal chest plague, decreasing regurgitation, and vomiting (P < 0.0002); SNZJD plus traditional stomach medicines(SPTSM)could by and large lessen full-scale sign scores with liberal ampleness (P < 0.00002). The replication degree and antagonistic effects regarding Sacroiliac Joint Dysfunction(SJD)treatment were basic. As confirmed through the TSA regarding thorough assessment, the results were significant, yet repeat security consequences were uncertain. As shown by the computation of the Grading of Recommendations Assessment, Development and Evaluation(GRADE)strategy, the idea regarding verification was minimal. Moreover, Schizoaffective disorder(SZD)may treat Gastrointestinal ebb ailment by presenting the onsetof the infection and controlling factors that may contribute to Gastrointestinal ebb ailments.Conclusion:The research evaluated the efficiency of Sini Zuojin Decoction in treating patients suffering from Gastrointestinal Ebb Ailments. [Ethiop. J. Health Dev.2022: 36(2) (00-00)]

Comparison between herbs used for the treatment of gastroesophageal reflux diseases (GERD)

Background:An abnormality that causes reflux is termed as Gastroesophageal reflux disease (GERD), which is symptomatic by nature and adds to the long-term effects.Objective:The aim of this study is to observe and monitor the effects of a herbal ttratment of GERD with SiniZuojin Decoction (SNZID)and to assess its mediation impacts regarding the use of the medication in patients with Gastrointestinal EBB ailment.Materials and Methods:The cohort research methodology was used inthe study.The research included 2581 individual patients who were older than 18 years of age and were suffering from Gastrointestinal ebbailment. The patients were selected from various government herbal clinics in eastern China, including the states of Anhui, Fujian, Jiangsu, Jiangxi, Shandong, and Zhejiangover, from 2008 to 2018. Results:The study was conducted with a total of 2581 patients. The thorough assessment indicated that Sini Zuojin Decoction (SZD)notwithstanding standard stomach remedies pack was more effective than the traditionalist stomach suppositories bundle (RR=1.34, with CI=95% [1.47, 1.38], and P-value = 0.008); Test packs including SZD was essentially better contrasted with traditional stomach medicines(TSM)gearshifts in developing dyspepsia, substernal chest plague, decreasing regurgitation, and vomiting (P < 0.0002); SNZJD plus traditional stomach medicines(SPTSM)could by and large lessen full-scale sign scores with liberal ampleness (P < 0.00002). The replication degree and antagonistic effects regarding Sacroiliac Joint Dysfunction(SJD)treatment were basic. As confirmed through the TSA regarding thorough assessment, the results were significant, yet repeat security consequences were uncertain. As shown by the computation of the Grading of Recommendations Assessment, Development and Evaluation(GRADE)strategy, the idea regarding verification was minimal. Moreover, Schizoaffective disorder(SZD)may treat Gastrointestinal ebb ailment by presenting the onsetof the infection and controlling factors that may contribute to Gastrointestinal ebb ailments.Conclusion:The research evaluated the efficiency of Sini Zuojin Decoction in treating patients suffering from Gastrointestinal Ebb Ailments. [Ethiop. J. Health Dev.2022: 36(2) (00-00)]Keywords:GERD, Esophagitis, Sini Zuojin Decoction(SZD), Gastrointestinal ebb ailment;

Five-year Prevalence of Gastrointestinal Diseases and Disorders in Akure South, Nigeria

The burden of gastrointestinal diseases and disorders (GIDD) remains high in Nigeria and varies across regions. This study wa s therefore designed to examine the prevalence of gastrointestinal diseases and disorders over a period of 5-years from January 2014 to December 2018 in Akure South of Ondo state, Nigeria. Descriptive retrospective study was employed and the medical records of all patients diagnosed for GIDD in the two selected health facilities were reviewed within the study period. In total, 12,323 medical records of patients with GIDD were included in this study. The prevalence of GIDD were 44.9% in the year 2014 with the lowest prevalence of 6.7% occurring in the year 2018. Over the 5-years period, lower GIDD cases were 91% compared to upper GIDD that was 9%. Peptic ulcer had the highest prevalence (55%) of lower GIDD followed by gastroenteritis (30%). Hiatal hernia had the highest prevalence (84%) for upper GIDD followed by dyspepsia (11%) and Gastroesophageal reflux disease (5%). Over a 5-year period, the prevalence of gastrointestinal disease and disorders in Akure south in this study shows that lower GIDD is more prevalent in the study area with peptic ulcer as the most predominant GIDD among the study population.

Etude de la prise en charge de l'infection à Helicobacter Pylori dans les villes de Pointe-Noire et de Brazzaville en 2015

Introduction : L'infection à Helicobacter Pylori affecte environ 50% de la population mondiale. Sa prévalence est plus élevée dans les pays en développement. Elle est à l'origine de pathologies gastroduodénales et son éradication est de ce fait recommandée.Nous avons réalisé une étude dont l'objectif a été d'évaluer les possibilités diagnostiques, thérapeutiques et la séroprévalence de l'infection à Helicobacter pylori dans les villes de Pointe-Noire et Brazzaville.Méthodes: Etude transversale descriptive et analytique menée de mars à septembre 2015.Résultats : Sur (7) sept tests existants et validés dans le monde; seuls (4) quatre tests étaient disponibles. La non disponibilité du test respiratoire à l'urée marquée au carbone 13 était à l'origine du non contrôle de l'éradication après traitement. Les protocoles d'éradication étaient la quadrithérapie séquentielle ou continue sur 10 jours sans sel de bismuth, non disponible au Congo-Brazzaville.Au total 130 patients ont été inclus; 54(41,5%) hommes et 76 (58,5%) femmes dont 121 (93,1%) patients étaient testés positifs à l'helicobacter pylori, avec une prédominance féminine. Le reflux gastro-oesophagien était la pathologie la plus représentée chez les patients testés positifs mais sans différence significative (P=0,287).Conclusion: L'insuffisance des tests diagnostiques de l'infection à Helicobacter pylori notamment du test respiratoire à l'urée marquée au carbone 13 au Congo-Brazzaville ne permettait pas aux praticiens de contrôler l'éradication. La quadrithérapie bismuthée n'était non plus disponible alors que la séroprévalence hospitalière reste élevée. Ainsi nous faisons le plaidoyer pour l'acquisition du test respiratoire à l'urée marquée au carbone 13 et la mise sur le marché des sels de Bismuth au Congo-Brazzaville

Myotomie de Heller par voie transthoracique : une experience monocentrique au Mali de 21 cas

But : Evaluer les resultats a mi-parcours de l'osocardiomyotomie de Heller par voie transthoracique avec la mise en place du systeme anti-reflux par un lambeau diaphragmatique pour le megaoesophage idiopathique. Patients et methodes : Il s'agissait d'une etude prospective ayant concerne 21 patients (14 femmes et 7 hommes) operes pour un megaoesophage idiopathique durant une periode de 3 ans. La voie d'abord a ete la voie transthoracique gauche pour tous nos patients. Un systeme anti-reflux avait ete realise en utilisant un lambeau diaphragmatique sur toute la longueur de la myotomie de l'oesophage thoracique. Resultats : L'age moyen etait de 32 ans (extremes : 16 et 68 ans). Les suites immediates etaient simples. Apres l'intervention nous avons assiste a une disparition complete de la dysphagie chez 21 patients (100 %) (p 0;001) et une reprise ponderale consequente. Les suites a court terme etaient marquees par la survenue d'un reflux gastro-osophagien clinique chez 1 patient (4.76 %) qui avait beneficie d'un systeme anti-reflux (p 0;05). Conclusion : L'osocardiomyotomie de Heller par voie transthoracique associee a la mise en place systematique d'un systeme anti-reflux par lambeau diaphragmatique donne de bons resultats

Gastro-Oesophageal Reflux in Infants and Children

Gastro-oesophageal reflux is a normal physiological phenomenon that is frequently associated with regurgitation in infants. In general; it resolves by the age of one year. Some children are more likely to have persistent symptoms and develop complications; e.g. children with congenital abnormalities of the oesophagus; neurological impairment; and a family history of gastro-oesophageal reflux disease (GORD). Preliminary evidence suggests that GORD in infancy and childhood may be a precursor to adult GORD. GORD is reflux that is associated with troublesome symptoms or complications. These complications are categorised into oesophageal and extra-oesophageal difficulties. Diagnosis in most patients relies on a thorough history and physical examination. However; the symptoms in infants and young children are often atypical. Patients with significant symptoms require more extensive diagnostic assessment; such as contrast radiography; oesophagoscopy and oesophageal pH-metry. In most cases; parental reassurance and advice on feeding are sufficient. Thickened feeds reduce the frequency of regurgitation. Patients with complications require potent acid inhibition and occasionally anti-reflux surgery

Manifestations ORL du reflux gastro-oesophagien

Cet article presente l'ensemble des pathologies qu'entraine un passage a travers le cardia du contenu gastrique dans l'oesophage. Il est essentiellement du a: un dysfonctionnement des mecanismes antireflux gastro-oesophagien; l'action corrosive des secretions digestives sur l'oesophage; une sensibilisation particuliere de la muqueuse oesophagienne. D'autres facteurs peuvent etre associes tel que le ralentissement de l'evacuation gastrique. C'est grace au developpement des moyens d'exploration qu'ont pu relies RGO et manifestations ORL

Echographie dans le reflux gastro-oesophagien du nouveau-ne et du nourrisson: experience du CHU de Yopougon (Cote d'Ivoire)

53 enfants dont 23 filles et 30 garcons provenent du service de Pediatrie ont ete explores a l'echographie a la recherche d'un RGO; sur une periode de 3 ans. Cette etude realisee dans le service de Radiologie du CHU de Yopougon d'Abidjan; a pour but d'affirmer la realite du RGO chez nous et de determiner les anomalies de la jonction oesocardio-tuberositaire par la methode echographique. La demande de l'examen echographique a ete motivee par une amnese et un examen clinique orientant vers une pathologie de reflux. L'etude echographique a permis la mise en evidence de 26;4 per cent de reflux pathologue. Des anomalies morphologiques ont ete notees dans 8 cas (57;1 per cent); essentiellement representees par la beance du cardia et la malposition cardiale. Cet examen apparait interessant dans le diagnostic de RGO et merite une meilleure diffusion du fait de ses avantages multiples alliant faible cout; non irradiation; efficacite et sensibilite. Aussi; les auteurs proposent-ils une meilleure vulgarisation de cette methode